SAM-e & TMG Lemon (30-Servings) – Xymogen

Overview

Xymogen’s SAM-e & TMG Lemon is a tangy, lemon-flavored powdered formula that delivers key methyl-donors — S-adenosyl-L-methionine (SAM-e) and TMG (trimethylglycine) — in a convenient daily stick pack. Designed to support vital methylation pathways, this supplement promotes healthy neurotransmitter production, liver function, glutathione synthesis, and joint comfort.

Key Features & Benefits

Methyl Donor Support

SAM-e and TMG are both strong methyl donors, helping to supply methyl groups for critical biochemical reactions like DNA/RNA synthesis, phospholipid formation, and protein methylation.

Mood & Neurotransmitter Synthesis

SAM-e contributes to neurotransmitter production (e.g., dopamine, serotonin) supporting a healthy mood and balanced brain chemistry.

Liver & Antioxidant Support

This formulation supports glutathione production via methylation and transsulfuration pathways, which may help maintain liver health and antioxidant defense.

Joint Comfort

SAM-e has been associated with joint-support effects, helping promote normal joint function and comfort.

High-Quality Isomer Form

Xymogen’s SAM-e contains a minimum of 70% SS isomer — the biologically active form — making it more bioavailable and cost-efficient compared to many lower-isomer products. 

Who It's For

This product is ideal for individuals who want to support their body’s methylation processes — including mood regulation, liver health, and joint function. It may be especially useful for people concerned about maintaining normal homocysteine levels, supporting glutathione production, or bolstering neurotransmitter synthesis.

How It Fits Into a Healthy Routine

Take one 2.6 g stick pack daily, preferably away from meals. You can dissolve it directly in your mouth or add it to 2–4 oz of water (or another beverage) and drink within 15 minutes.
Because it supports methylation, some practitioners pair it with B-complex vitamins, but always consult with your healthcare provider before combining supplements.

What’s Inside (Supplement Facts)

Here’s a breakdown of the main active nutrients per serving:

Other Ingredients: xylitol, citric acid, malic acid, natural lemon flavor, silica, stearic acid, and a touch of turmeric extract for color. 
Allergen / Free-From Info: Gluten-free, dairy-free, soy-free, egg-free, non-GMO, no artificial sweeteners, no artificial colors. 

Warnings: Consult a healthcare professional before use, especially if you’re on medication or have mood disorders such as bipolar disorder.