Xymogen Berberine ES-5 Duo (60 Vegetarian Capsules)

Overview

Xymogen Berberine ES-5 Duo is a premium trace botanical formula designed to support healthy blood-glucose metabolism and glycemic response. It features a highly bioavailable metabolite of berberine (dihydroberberine) combined with a polyphenol-rich brown seaweed extract and trace chromium to help maintain normal carbohydrate processing and metabolic balance. According to the manufacturer, the formulation says it offers “5× the bioavailability of berberine”. 

Key Features & Benefits

High-Bioavailability Dihydroberberine (DHB)

Each capsule supplies 100 mg of dihydroberberine, a metabolite of berberine that is claimed to be more easily absorbed than standard berberine. This higher bioavailability supports the formula’s goal of aiding healthy glucose metabolism and glycemic response.

Brown Seaweed Polyphenol Blend (InSea2®) + Chromium

The formulation also contains 250 mg of a brown seaweed blend (Ascophyllum nodosum & Fucus vesiculosus) rich in polyphenols that may help slow carbohydrate breakdown, along with 7.5 mcg chromium (as chromium nicotinate glycinate chelate) to support trace-mineral metabolism. Together, these support the formulation’s stated purpose of “supporting a healthy glycemic response to foods”. 

Who It’s For

This product is suited for adult individuals wanting to support normal blood-glucose metabolism, healthy insulin sensitivity, and improved carbohydrate processing as part of a wellness routine. It is not intended to diagnose, treat, or cure any medical condition—users should consult a qualified healthcare professional, especially if they are taking medications or have underlying health issues.

How It Fits Into a Healthy Routine

Take one vegetarian capsule twice daily before meals (or as directed by your healthcare professional) to support optimal timing around carbohydrate intake. Pairing this formula with balanced meals (including fiber, healthy fats and lean protein), physical activity, and overall metabolic wellness habits enhances its practical fit into everyday routines.
Because the product involves metabolic support, those using medications for glucose regulation should coordinate with their healthcare provider before supplementing.

What’s Inside

Key Ingredients per Serving (1 capsule):

• Dihydroberberine (100 mg) — a metabolite of berberine, designed for enhanced bioavailability. 

• Brown Seaweed Blend (250 mg) — polyphenol-rich extract from Ascophyllum nodosum & Fucus vesiculosus. 

• Chromium (7.5 mcg as chromium nicotinate glycinate chelate) — trace mineral support for carbohydrate metabolism. 

• Other ingredients: hypromellose capsule, microcrystalline cellulose, ascorbyl palmitate, silica. 

• Free of: wheat, gluten, yeast, soy, dairy, fish/shellfish, tree nuts, eggs, peanuts, sesame, GMOs, artificial colors/sweeteners.